Molecular Biology of B Cells

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Contenidos del Libro:

1. Human Immunoglobulin Heavy Chain Locus
   
2. Immunoglobulin Heavy Chain Genes of Mouse
   
3. Immunoglobulin K Genes of Human and Mouse
   
4. Immunoglobulin Lambda (IGL) Genes of Human and Mouse
   
5. The Mechanisms of V(D)J Recombination
   
6. Transcription of Immunoglobulin Genes
   
7. Early B Cell Development to a Mature, Antigen-Sensitive Cell
   
8. Allelic Exclusion, Isotypic Exclusion, and the Developmental Regulation of V(D)J Recombination
   
9. The Development of Human B Lymphocytes
   
10. Development and Function of B Cell Subsets
    
11. Structure and Function of B Cell Antigen Receptor Complexes
    
12. Regulation of Antigen Receptor Signaling by the Co-Receptors, CD19 and CD22
    
13. The Dynamic Structure of Antibody Responses
    
14. Dynamics of B Cell Migration to and within Secondary Lymphoid Organs
    
15. Characteristics of Mucosal B Cells with Emphasis on the Human Secretory Immune System
    
16. The Cellular Basis of B Cell Memory
    
17. Immunoglobulin Assembly and Secretion
    
18. Fc and Complement Responses
    
19. Regulation of Class Switch Recombination
    
20. Molecular Mechanisms of Class Switch Recombination
    
21. Molecular Mechanisms of Hypermutation
    
22. Selection During Antigen-Driven B Cell Immune Responses: The Basis for High Affinity Antibody
    
23. Chromosomal Translocations in B Cell Leukemias and Lymphomas
    
24. Classification and Characteristics of Mouse B Cell–Lineage Lymphomas
    
25. B Cells Producing Pathogenic Autoantibodies
    
26. Immunodeficiencies Caused by B Cell Defects
    
27. Diverse Forms of Immunoglobulin Genes in Lower Vertebrates
    
28. Immunoglobulin Genes and Generation of Antibody Repertoires in Higher Vertebrates: A Key Role for GALT
    
29. The Zebrafish Immune System
    
30. The Origin of V(D)J Diversification
    
31. Antibody Structure and Recognition of Antigen
    
32. Monoclonal Antibodies from Display Libraries
    
33. Humanization of Monoclonal Antibodies
    
34. Human Monoclonal Antibodies from Translocus Mice
    

Handbook of Vertebrate Immunology

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Hace varios meses un visitante del blog me pidió info sobre Inmunología de peces, que evidentemente no he podido encontrar, pero en su defecto subo este otro que es bastante bueno.

Como podrán darse cuenta el libro abarca casi todas las Clases de Vertebrados (faltan los Chondrichthyes (rayas y tiburones)). Describe principalmente la Inmunidad en mamíferos, desglosandolos en varios capítulos; este "exceso" de mamíferos se debe a que la mayoria de los estudios están hechos en estos animales, y por ende hay más información.

Contenidos del Libro:

1. Introduction
   
2. Immunology of Fishes
   
3. Immunology of Amphibians
   
4. Avian Immunology
   
5. Immunology of the Rat
   
6. Immunology of Lagomorphs
   
7. Immunology of the Dog
   
8. Immunology of the Cat
   
9. Immunology of Mustelidae
   
10. Immunology of Horses and Donkeys
    
11. Immunology of the Pig
    
12. Immunology of Camels and Llamas
    
13. Immunology of Cattle
    
14. Sheep Immunology and Goat Peculiarities
    
15. Immunology of Buffalo
    
16. The Mouse Model
    
17. The Scid Mause Mutant: Definition and Potencial Use as a Model for Immnune Disorders
    
18. Xenotransplantation

PD.: Para aquellos que nunca han tenido un ramo de Zoología, les explico: los Lagomorfos son todos los conejos y liebres (en términos correctos, aquellos que tienen 2 pares de  incisivos superiores), y los mustelidos son una familia de carnívoros, tanto terrestres como acuaticos, a la que pertenecen los hurones, tejones, lirones, nutrias y los nunca bien ponderados "Glotones", o en su nombre en inglés "Wolverine" (para los amantes del comics, jaja).

The Macrophage

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Contenidos del Libro:

1. The biology of the macrophage
   
2. Molecular basis of macrophage activation: from gene expression to phenotypic diversity
   
3. Macrophages as antigen-presenting cells: relationship to dendritic cells and use in vaccination studies
   
4. Macrophage–virus interactions
   
5. Macrophages in bacterial infection
   
6. Macrophages in parasitic infection
   
7. Macrophages and Alzheimer’s disease
   
8. Macrophages in autoimmunity and primary immunodeficiency
   
9. Macrophages in rheumatoid arthritis
   
10. Macrophages in wound healing
    
11. Macrophages in tumor biology
    
12. Macrophages in cardiovascular disease
    
13. Macrophages in the central nervous system
    
14. Macrophages in reproductive biology
    
15. Macrophages in gene therapy: cellular targets and gene delivery vehicles
    
16. Use of mathematical models to simulate and predict macrophage activity in diseased tissues
    

Mast Cells and Basophils

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Contenidos del Libro:

Part 1: DEVELOPMENT OF MAST CELLS AND BASOPHILS

1.- Regulation of Mast Cell and Basophil Development by Stem Cell Factor and Interleukin-3

2.- Gain-of-function Mutations of c-kit in Human Diseases

3.- Modulation of Mast Cell Development from Embryonic Haematopoietic Progenitors by Eotaxin

4.- Regulation and Dysregulation of Mast Cell Survival and Apoptosis

Part 2: PHENOTYPIC AND ULTRASTRUCTURAL FEATURES OF MAST CELLS AND BASOPHILS

5.- Ultrastructural Features of Human Basophil and Mast Cell Secretory Function

6.- Human Dendritic Mast Cells 

7.- The Phenotypic Similarities and Differences Between Human Basophils and Mast Cells

8.- Interactions Between Nerves and Mast Cells in Amphibians

Part 3: SIGNAL TRANSDUCTION IN MAST CELLS AND BASOPHILS

9.- Sequential Protein Kinase Activation and the Regulation of Mast Cell Cytokine Production

10.- Fc~RI-mediated Induction of TNF-o~ Gene Expression in Mast Cell Lines

11.- Regulation of Mast Cell Degranulation by SHIP

Part 4: REGULATION OF MAST CELL AND BASOPHIL SIGNALLING AND SECRETION

12.- Immunoreceptor Tyrosine-based Inhibition Motif-dependent Negative Regulation of Mast Cell Activation and Proliferation

13.- Perspectives on the Regulation of Secretion from Human Basophils and Mast Cells

14.- Interactions between Secretory IgA and Human Basophils

15.- Regulation of Mast Cell Secretion by Interferon-~/and Nitric Oxide

Part 5: STRUCTURE AND FUNCTION OF MAST CELL PROTEASES

16.- Human and Mouse Mast Cell Tryptases

17.- Expression, Function and Regulation of Mast Cell Granule Chymases During Mucosal Allergic Responses

18.- Structure and Function of Human Chymase

19.- Structure and Function of Human Mast Cell Tryptase

Part 6: NERVE-MAST CELL INTERACTIONS: PHYSIOLOGY AND PATHOLOGY

20.- Mast Cell-Nerve Interactions: Possible Significance of Nerve Growth Factor

21.- Nerve Growth Factor, Mast Cells and Allergic Inflammation

22.- Interactions Between Neurotrophins and Mast Cells

23.- Modulation of Peripheral Neurotransmission Associated with Mast Cell Activation

24.- Regulation of Gastrointestinal Mucin Production by Nerve-Mast Cell Interactions

Part 7: MAST CELLS AND BASOPHILS IN HOMEOSTASIS AND HOST DEFENCE

25.- Mast Cell-Enterobacteria Interactions during Infection

26.- Human Mast Cells and Basophils in Immune Responses to Infectious Agents

27.- Differential Regulation of Mast Cell Mediator Secretion by Bacterial Products

28.- The Role of Mast Cells, Basophils and Interleukin-3 (IL-3) in Immune Responses to Parasites: Studies with Mast Cell- and IL-3-Deficient Mice

Part 8: MAST CELLS IN ATHEROSCLEROSIS AND CARDIAC DISEASES

29.- Human Heart Mast Cells: Immunological Characterization In Situ and In Vitro

30.- Mast Cells in Atherosclerotic Human Coronary Arteries: Implications for Coronary Fatty Streak Formation, Plaque Ulceration and Control of Local Haemostatic Balance

31.- Role of Mast Cells in Endogenous Fibrinolysis and Related (Patho)physiological Processes

32.- Mast Cells in Myocardial Ischaemia and Reperfusion

Part 9: LEUKOTRIENES, CYTOKINES AND CHEMOKINES IN ALLERGIC DISORDERS

33.- Lipid Mediators from Mast Cells and Basophils in Allergic Diseases

34.- Regulation and Function of Human Intestinal Mast Cells

35.- Differential Regulation of Basophil Functions by Chemokines

36.- Chemokine Receptors on Human Mast Cells

37.- Release and Cleavage of Stem Cell Factor by Human Mast Cells

38.- SCF-Induced Chemokine Production, Allergic Airway Inflammation and Airway Hyper-reactivity

Part 10: CLINICAL IMPLICATIONS OF HISTAMINE H1 RECEPTOR ANTAGONISTS

39.- Pharmacological Profile of Mizolastine, a Novel Histamine H1 Receptor Antagonist

40.- Adenosine-Induced Enhancement of Mast Cell Mediator Release in Asthma and COPD 

41.- Neural Activation and Inflammation in Allergic Rhinitis

42.- Antihistaminic and Anti-inflammatory Effects of Mizolastine

43.- Electrophysiological and Molecular Basis for the Adverse Cardiovascular Effects of Histamine H, Receptor Antagonists

Dendritic Cells

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Contenidos del Libro:

Part I: Biology of Dendritic Cells

1.- Activation of Dendritic Cells by Toll-Like Receptors and C-Type Lectins

2.- Dendritic Cell Migration to Peripheral Lymph Nodes

Part II: Role of Dendritic Cells in Disease

3.- Dendritic Cells and their Potential Implication in Pathology and Treatment of Rheumatoid Arthritis

4.- Lung Dendritic Cells: Targets for Therapy in Allergic Disease

5.- Dendritic Cells in Rhinitis

6.- Role of Epidermal Dendritic Cells in Drug-Induced Cutaneous Adverse Reactions

Part III: Manipulation of Dendritic Cells for Immunotherapy

7.- T Cell Regulatory Plasmacytoid Dendritic Cells Expressing Indoleamine 2,3 Dioxygenase

8.- Aspirin and the Induction of Tolerance by Dendritic Cells

9.- Use of Rapamycin in the Induction of Tolerogenic Dendritic Cells

10.- Handbook of Experimental Pharmacology “Dendritic Cells”

11.- Induction of Tolerogenic Dendritic Cells by Vitamin D Receptor Agonists

12.- Use of Adenovirus in Vaccines for HIV

13.- IFN-alpha in the Generation of Dendritic Cells for Cancer Immunotherapy

14.- Dendritic Cell-Based Immunotherapy in Myeloid Leukaemia: Translating Fundamental Mechanisms into Clinical Applications

Último libro de DCs que subo... aprovecho el impulso para subir otro par de libros sobre Células del Sistema Inmune.

Saludos.

Azabett.